USMLE Online Practice Questions and Answers

A couple presents to a clinic for workup of infertility after 5 years of unprotected intercourse. The wife denies any medical problems and notes regular menstrual cycles. The husband states that he has had chronic sinusitis and lower respiratory tract infections. Physical examination of the woman is unremarkable. Examination of the man is remarkable for dextrocardia. Further workup of the husband will most likely reveal

A. azoospermia

B. germinal cell aplasia

C. immotile sperm

D. isolated gonadotropin deficiency

E. varicocele

A sexually active 23-year-old man with multiple sex partners has dysuria and a yellow urethral exudate. Gram stain of the exudate shows numerous neutrophils, many that contain intracellular gram-negative diplococci. He has had three similar episodes of urethritis over the past 2 years. Which of the following properties of the infecting organism best explains the reinfection?

A. Antigenic variation

B. Catalase

C. Inhibition of B-lymphocyte function

D. Inhibition of T-lymphocyte function

E. Polysaccharide capsule

A 22-year-old woman comes to the office because of a 3-day history of cold symptoms and a 1-week history of progressive fatigue. Six weeks ago, she received a kidney transplant from a living, related donor. Immediately after the operation, she received monoclonal anti-CD3 therapy. Current medications are azathioprine, cyclosporine, and prednisone. Her temperature is 39°C (102.2°F). Physical examination shows a well-healed surgical scar. Serum studies show that her urea nitrogen and creatinine concentrations have tripled. A diagnosis of allograft rejection is suspected. In addition, this patient's clinical presentation is best explained by an infection with which of the following agents?

A. Adenovirus

B. BK virus

C. Epstein-Barr virus

D. Herpes simplex virus

E. Varicella-zoster virus

A 31-year-old woman comes to the physician because of a 2-week history of malaise, nausea, vomiting, and decreased appetite. She is a known user of intravenous heroin. She appears chronically ill. She is 165 cm (5 ft 5 in) tall and weighs 47kg (103 lb); BMI is 17 kg/m2. Her temperature is 36.7°C (98.1°F), pulse is 90/min, respirations are 18/min, and blood pressure is 114/68 mmHg. Physical examination shows scleral icterus and a liver span of 16 cm. The spleen is not palpable. Serum studies show: Which of the following is the most likely outcome of this patient's infection?

A. Complete resolution of infection

B. Latent infection with intermittent viremia

C. Lifelong persistent infection

D. Patient death from acute infection

Which of the following is not directly related with Kawasaki disease?

A. Lymphadenitis

B. Fever

C. Arthritis

D. Conjunctiva

Lansoprazole is not used in which of the following cases?

A. Gastritis

B. Peptic Ulcers

C. Zollinger-Ellison syndrome

D. Thalamus hypertrophy

Which of the following is not a function of Estrogen?

A. Causes breast growth.

B. Causes inhibition of FSH

C. Increased follicle development

D. Decreased overall transport proteins

Which of the following is not considered a part of the male urethra?

A. Prostatic

B. Membranous

C. Vasapore

D. Penile

The one of the functions occurring at the distal convoluted tubule in the kidney is?

A. Passive secretion of hydrogen ions

B. Passive secretion of potassium ions

C. Limited re-absorption of water

D. No re-absorption of sodium

Which of the following drugs may be given as an immunosuppressant soon after onset of Type I Diabetes?

A. Torsemide

B. Cyclosporine

C. Clofibrate

D. Ceftriaxone